Pericentromeric satellite repeat expansions through RNA-derived DNA intermediates in cancer

Aberrant transcription of the pericentromeric human satellite II (HSATII) repeat is present in a wide variety of epithelial cancers. In deriving experimental systems to study its deregulation, we observed that HSATII expression is induced in colon cancer cells cultured as xenografts or under nonadhe...

詳細記述

保存先:
書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Bersani, Francesca, Lee, Eunjung, Kharchenko, Peter V., Xu, Andrew W., Liu, Mingzhu, Xega, Kristina, MacKenzie, Olivia C., Brannigan, Brian W., Wittner, Ben S., Jung, Hyunchul, Ramaswamy, Sridhar, Park, Peter J., Maheswaran, Shyamala, Ting, David T., Haber, Daniel A.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2015
主題:
Biological Sciences
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679016/
https://ncbi.nlm.nih.gov/pubmed/26575630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1518008112
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