Amyloid fibrils activate B-1a lymphocytes to ameliorate inflammatory brain disease

Amyloid fibrils composed of peptides as short as six amino acids are therapeutic in experimental autoimmune encephalomyelitis (EAE), reducing paralysis and inflammation, while inducing several pathways of immune suppression. Intraperitoneal injection of fibrils selectively activates B-1a lymphocytes...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Kurnellas, Michael Phillip, Ghosn, Eliver Eid Bou, Schartner, Jill M., Baker, Jeanette, Rothbard, Jesse J., Negrin, Robert S., Herzenberg, Leonore A., Fathman, C. Garrison, Steinman, Lawrence, Rothbard, Jonathan B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2015
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679000/
https://ncbi.nlm.nih.gov/pubmed/26621719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1521206112
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