Identifying gene-gene interactions that are highly associated with Body Mass Index using Quantitative Multifactor Dimensionality Reduction (QMDR)

BACKGROUND: Despite heritability estimates of 40–70 % for obesity, less than 2 % of its variation is explained by Body Mass Index (BMI) associated loci that have been identified so far. Epistasis, or gene-gene interactions are a plausible source to explain portions of the missing heritability of BMI...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:BioData Min
Main Authors: De, Rishika, Verma, Shefali S., Drenos, Fotios, Holzinger, Emily R., Holmes, Michael V., Hall, Molly A., Crosslin, David R., Carrell, David S., Hakonarson, Hakon, Jarvik, Gail, Larson, Eric, Pacheco, Jennifer A., Rasmussen-Torvik, Laura J., Moore, Carrie B., Asselbergs, Folkert W., Moore, Jason H., Ritchie, Marylyn D., Keating, Brendan J., Gilbert-Diamond, Diane
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4678717/
https://ncbi.nlm.nih.gov/pubmed/26674805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13040-015-0074-0
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados