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Multifactor dimensionality reduction: An analysis strategy for modelling and detecting gene - gene interactions in human genetics and pharmacogenomics studies

The detection of gene - gene and gene - environment interactions associated with complex human disease or pharmacogenomic endpoints is a difficult challenge for human geneticists. Unlike rare, Mendelian diseases that are associated with a single gene, most common diseases are caused by the non-linea...

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Detalhes bibliográficos
Main Authors: Motsinger, Alison A, Ritchie, Marylyn D
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500181/
https://ncbi.nlm.nih.gov/pubmed/16595076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-7364-2-5-318
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