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A Comparison of Multifactor Dimensionality Reduction and L(1)-Penalized Regression to Identify Gene-Gene Interactions in Genetic Association Studies*

Recently, the amount of high-dimensional data has exploded, creating new analytical challenges for human genetics. Furthermore, much evidence suggests that common complex diseases may be due to complex etiologies such as gene-gene interactions, which are difficult to identify in high-dimensional dat...

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Detalhes bibliográficos
Main Authors: Winham, Stacey, Wang, Chong, Motsinger-Reif, Alison A
Formato: Artigo
Idioma:Inglês
Publicado em: Berkeley Electronic Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045083/
https://ncbi.nlm.nih.gov/pubmed/21291414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2202/1544-6115.1613
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