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Ribosome Subunit Stapling for Orthogonal Translation in E. coli

The creation of orthogonal large and small ribosomal subunits, which interact with each other but not with endogenous ribosomal subunits, would extend our capacity to create new functions in the ribosome by making the large subunit evolvable. To this end, we rationally designed a ribosomal RNA that...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Fried, Stephen D, Schmied, Wolfgang H, Uttamapinant, Chayasith, Chin, Jason W
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY-VCH Verlag 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4678508/
https://ncbi.nlm.nih.gov/pubmed/26465656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201506311
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