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Controlling orthogonal ribosome subunit interactions enables evolution of new function
Orthogonal ribosomes are unnatural ribosomes that are directed towards orthogonal messenger RNAs in Escherichia coli, through an altered version of the 16S ribosomal RNA of the small subunit1. Directed evolution of orthogonal ribosomes has provided access to new ribosomal function, and the evolved o...
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| Izdano u: | Nature |
|---|---|
| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2018
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6525102/ https://ncbi.nlm.nih.gov/pubmed/30518861 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-018-0773-z |
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