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Ribosome Subunit Stapling for Orthogonal Translation in E. coli

The creation of orthogonal large and small ribosomal subunits, which interact with each other but not with endogenous ribosomal subunits, would extend our capacity to create new functions in the ribosome by making the large subunit evolvable. To this end, we rationally designed a ribosomal RNA that...

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Dades bibliogràfiques
Publicat a:Angew Chem Int Ed Engl
Autors principals: Fried, Stephen D, Schmied, Wolfgang H, Uttamapinant, Chayasith, Chin, Jason W
Format: Artigo
Idioma:Inglês
Publicat: WILEY-VCH Verlag 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4678508/
https://ncbi.nlm.nih.gov/pubmed/26465656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201506311
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