The TGFβ1 Promoter SNP C-509T and Food Sensitization Promote Esophageal Remodeling in Pediatric Eosinophilic Esophagitis

BACKGROUND: Eosinophilic esophagitis (EoE) is a chronic antigen mediated disease associated with substantial esophageal remodeling and fibrosis. The functional TGFβ1 promoter SNP C-509 associates with renal fibrosis and asthma. The effect of TGFβ1 genotype and EoE severity or potential gene-environm...

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Veröffentlicht in:PLoS One
Hauptverfasser: Rawson, Renee, Anilkumar, Arjun, Newbury, Robert O., Bafna, Vineet, Aquino, Melissa, Palmquist, Jacob, Hoffman, Hal M., Mueller, James L., Dohil, Ranjan, . Broide, David H, Aceves, Seema S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4678166/
https://ncbi.nlm.nih.gov/pubmed/26656423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144651
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