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The α-arrestin ARRDC3 mediates ALIX ubiquitination and G protein–coupled receptor lysosomal sorting

The sorting of G protein–coupled receptors (GPCRs) to lysosomes is critical for proper signaling and cellular responses. We previously showed that the adaptor protein ALIX regulates lysosomal degradation of protease-activated receptor-1 (PAR1), a GPCR for thrombin, independent of ubiquitin-binding E...

詳細記述

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書誌詳細
出版年:Mol Biol Cell
主要な著者: Dores, Michael R., Lin, Huilan, J. Grimsey, Neil, Mendez, Francisco, Trejo, JoAnn
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Cell Biology 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4678022/
https://ncbi.nlm.nih.gov/pubmed/26490116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-05-0284
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