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Molecular mechanism and cellular function of MHCII ubiquitination

The major histocompatibility complex class II (MHCII) is ubiquitinated via the evolutionally conserved lysine in the cytoplasmic tail of the β chain in dendritic cells (DCs) and B cells. The ubiquitination is mediated by the membrane-associated RING-CH1 (MARCH1) ubiquitin ligase although it can be a...

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Detalhes bibliográficos
Publicado no:Immunol Rev
Main Authors: Oh, Jaehak, Shin, Jeoung-Sook
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4677682/
https://ncbi.nlm.nih.gov/pubmed/26085212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12303
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