Myeloperoxidase–Hepatocyte–Stellate Cell Cross Talk Promotes Hepatocyte Injury and Fibrosis in Experimental Nonalcoholic Steatohepatitis

Aims: Myeloperoxidase (MPO), a highly oxidative enzyme secreted by leukocytes has been implicated in human and experimental nonalcoholic steatohepatitis (NASH), but the underlying mechanisms remain unknown. In this study, we investigated how MPO contributes to progression from steatosis to NASH. Res...

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Dades bibliogràfiques
Publicat a:Antioxid Redox Signal
Autors principals: Pulli, Benjamin, Ali, Muhammad, Iwamoto, Yoshiko, Zeller, Matthias W.G., Schob, Stefan, Linnoila, Jenny J., Chen, John W.
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2015
Matèries:
Original Research Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4677570/
https://ncbi.nlm.nih.gov/pubmed/26058518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2014.6108
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