The Interplay Between Peroxiredoxin-2 and Nuclear Factor-Erythroid 2 Is Important in Limiting Oxidative Mediated Dysfunction in β-Thalassemic Erythropoiesis

Aims: β-Thalassemia is a common inherited red cell disorder characterized by ineffective erythropoiesis and severe oxidative stress. Peroxiredoxin-2 (Prx2), a typical 2-cysteine peroxiredoxin, is upregulated during β-thalassemic erythropoiesis, but its contribution to stress erythropoiesis, a common...

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Dettagli Bibliografici
Pubblicato in:Antioxid Redox Signal
Autori principali: Matte, Alessandro, De Falco, Luigia, Iolascon, Achille, Mohandas, Narla, An, Xiuli, Siciliano, Angela, Leboeuf, Christophe, Janin, Anne, Bruno, Mariasole, Choi, Soo Young, Kim, Dae Won, De Franceschi, Lucia
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2015
Soggetti:
Original Research Communications
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4677567/
https://ncbi.nlm.nih.gov/pubmed/26058667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2014.6237
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