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Combined cardiomyocyte PKCδ and PKCε gene deletion uncovers their central role in restraining developmental and reactive heart growth

Cell growth is orchestrated by changes in gene expression that respond to developmental and environmental cues. Among the signaling pathways that direct growth are enzymes of the protein kinase C (PKC) family, which are ubiquitous proteins belonging to three distinct subclasses: conventional PKCs, n...

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Bibliographic Details
Published in:Sci Signal
Main Authors: Song, Moshi, Matkovich, Scot J., Zhang, Yan, Hammer, Daniel J., Dorn, Gerald W.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4677479/
https://ncbi.nlm.nih.gov/pubmed/25900833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaa1855
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