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Using Concatenated Subunits to Investigate the Functional Consequences of Heterotetrameric Inositol 1,4,5-Trisphosphate Receptors
Inositol 1,4,5-trisphosphate receptors (IP(3)R) are a family of ubiquitous, ER localized, tetrameric Ca(2+) release channels. There are 3 subtypes of the IP(3)Rs (R1, R2, R3), encoded by 3 distinct genes, that share ~60-70% sequence identity. The diversity of Ca(2+) signals generated by IP(3)Rs is t...
Gardado en:
| Publicado en: | Biochem Soc Trans |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4677331/ https://ncbi.nlm.nih.gov/pubmed/26009177 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20140287 |
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