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Using Concatenated Subunits to Investigate the Functional Consequences of Heterotetrameric Inositol 1,4,5-Trisphosphate Receptors

Inositol 1,4,5-trisphosphate receptors (IP(3)R) are a family of ubiquitous, ER localized, tetrameric Ca(2+) release channels. There are 3 subtypes of the IP(3)Rs (R1, R2, R3), encoded by 3 distinct genes, that share ~60-70% sequence identity. The diversity of Ca(2+) signals generated by IP(3)Rs is t...

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Detaylı Bibliyografya
Yayımlandı:Biochem Soc Trans
Asıl Yazarlar: Chandrasekhar, Rahul, Alzayady, Kamil J., Yule, David I.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4677331/
https://ncbi.nlm.nih.gov/pubmed/26009177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20140287
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