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Gene silencing of TACE enhances plaque stability and improves vascular remodeling in a rabbit model of atherosclerosis
We aimed to test the hypothesis that gene silencing of tumor necrosis factor alpha converting enzyme (TACE) may attenuate lesion inflammation and positive vascular remodeling and enhance plaque stability in a rabbit model of atherosclerosis. Lentivirus-mediated TACE shRNA was injected into the abdom...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4677302/ https://ncbi.nlm.nih.gov/pubmed/26655882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17939 |
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