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Silence of TRIB3 Suppresses Atherosclerosis and Stabilizes Plaques in Diabetic ApoE(−/−)/LDL Receptor(−/−) Mice

Insulin resistance triggers the developments of diabetes mellitus and atherosclerosis. Tribbles homolog 3 (TRIB3) is involved in insulin resistance. We aimed to investigate whether TRIB3 is implicated in diabetic atherosclerosis. Sixty 3-week-old apolipoprotein E (ApoE(−/−))/LDR receptor (LDLR(−/−))...

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Detalhes bibliográficos
Main Authors: Wang, Zhi-hao, Shang, Yuan-yuan, Zhang, Shun, Zhong, Ming, Wang, Xu-ping, Deng, Jing-ti, Pan, Jie, Zhang, Yun, Zhang, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266419/
https://ncbi.nlm.nih.gov/pubmed/22275087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-0518
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