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Urotensin-II-Mediated Reactive Oxygen Species Generation via NADPH Oxidase Pathway Contributes to Hepatic Oval Cell Proliferation

Urotensin II (UII), a somatostatin-like cyclic peptide, is involved in tumor progression due to its mitogenic effect. Our previous study demonstrated that UII and its receptor UT were up-regulated in human hepatocellular carcinoma (HCC), and exogenous UII promoted proliferation of human hepatoma cel...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Yu, XiaoTong, Wang, PengYan, Shi, ZhengMing, Dong, Kun, Feng, Ping, Wang, HongXia, Wang, XueJiang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4676694/
https://ncbi.nlm.nih.gov/pubmed/26658815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144433
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