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NADPH oxidase and reactive oxygen species contribute to alcohol-induced microglial activation and neurodegeneration
BACKGROUND: Activation of microglia causes the production of proinflammatory factors and upregulation of NADPH oxidase (NOX) that form reactive oxygen species (ROS) that lead to neurodegeneration. Previously, we reported that 10 daily doses of ethanol treatment induced innate immune genes in brain....
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2012
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3271961/ https://ncbi.nlm.nih.gov/pubmed/22240163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-5 |
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