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NADPH oxidase and reactive oxygen species contribute to alcohol-induced microglial activation and neurodegeneration

BACKGROUND: Activation of microglia causes the production of proinflammatory factors and upregulation of NADPH oxidase (NOX) that form reactive oxygen species (ROS) that lead to neurodegeneration. Previously, we reported that 10 daily doses of ethanol treatment induced innate immune genes in brain....

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Autori principali: Qin, Liya, Crews, Fulton T
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3271961/
https://ncbi.nlm.nih.gov/pubmed/22240163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-5
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