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Urotensin II-induced insulin resistance is mediated by NADPH oxidase-derived reactive oxygen species in HepG2 cells

AIM: To investigated the effects of urotensin II (UII) on hepatic insulin resistance in HepG2 cells and the potential mechanisms involved. METHODS: Human hepatoma HepG2 cells were cultured with or without exogenous UII for 24 h, in the presence or absence of 100 nmol/L insulin for the last 30 min. G...

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Bibliographische Detailangaben
Veröffentlicht in:World J Gastroenterol
Hauptverfasser: Li, Ying-Ying, Shi, Zheng-Ming, Yu, Xiao-Yong, Feng, Ping, Wang, Xue-Jiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Baishideng Publishing Group Inc 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4932212/
https://ncbi.nlm.nih.gov/pubmed/27433090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v22.i25.5769
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