Association of elevated α-defensin levels with interstitial pneumonia in patients with systemic sclerosis

BACKGROUND: Interstitial lung disease (ILD) is the leading cause of mortality in patients with systemic sclerosis (SSc). Although the pathogenesis of SSc-ILD is not well understood, neutrophils may play a pivotal role in this process. Neutrophils store azurophil granules that contain defensins, anti...

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Bibliographic Details
Published in:	Respir Res
Main Authors:	Sakamoto, Noriho, Kakugawa, Tomoyuki, Hara, Atsuko, Nakashima, Shota, Yura, Hirokazu, Harada, Tatsuhiko, Ishimoto, Hiroshi, Yatera, Kazuhiro, Kuwatsuka, Yutaka, Hara, Toshihide, Ichinose, Kunihiro, Obase, Yasushi, Ishimatsu, Yuji, Kohno, Shigeru, Mukae, Hiroshi
Format:	Artigo
Language:	Inglês
Published:	BioMed Central 2015
Subjects:	Research
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4676113/ https://ncbi.nlm.nih.gov/pubmed/26654954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-015-0308-1
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Association of elevated α-defensin levels with interstitial pneumonia in patients with systemic sclerosis

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