Elevated α-defensin levels in plasma and bronchoalveolar lavage fluid from patients with myositis-associated interstitial lung disease

BACKGROUND: Interstitial lung disease (ILD) is a prognostic indicator of poor outcome in myositis. Although the pathogenesis of myositis-associated ILD is not well understood, neutrophils are thought to play a pivotal role. Neutrophils store azurophil granules that contain defensins, which are antim...

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Detalhes bibliográficos
Publicado no:BMC Pulm Med
Main Authors: Sakamoto, Noriho, Ishimoto, Hiroshi, Kakugawa, Tomoyuki, Satoh, Minoru, Hasegawa, Tomoko, Tanaka, Shin, Hara, Atsuko, Nakashima, Shota, Yura, Hirokazu, Miyamura, Takuto, Koyama, Hanako, Morita, Towako, Nakamichi, Seiko, Obase, Yasushi, Ishimatsu, Yuji, Mukae, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5848598/
https://ncbi.nlm.nih.gov/pubmed/29530007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12890-018-0609-5
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