Oxidative Stress Alters the Morphology and Toxicity of Aortic Medial Amyloid

The aggregation and fibril deposition of amyloid proteins have been implicated in a range of neurodegenerative and vascular diseases, and yet the underlying molecular mechanisms are poorly understood. Here, we use a combination of cell-based assays, biophysical analysis, and atomic force microscopy...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biophys J
Hauptverfasser: Davies, Hannah A., Phelan, Marie M., Wilkinson, Mark C., Migrino, Raymond Q., Truran, Seth, Franco, Daniel A., Liu, Lu-Ning, Longmore, Christopher J., Madine, Jillian
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2015
Schlagworte:
Proteins and Nucleic Acids
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675884/
https://ncbi.nlm.nih.gov/pubmed/26636947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.10.034
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