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The Influence of Crowding Conditions on the Thermodynamic Feasibility of Metabolic Pathways

Intracellular reactions are carried out in a crowded medium where the macromolecules occupy ∼40% of the total volume. This decrease in the available volume affects the activity of the reactants. Scaled particle theory is used for the estimation of the activity coefficients of the metabolites, and th...

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Dettagli Bibliografici
Pubblicato in:Biophys J
Autori principali: Angeles-Martinez, Liliana, Theodoropoulos, Constantinos
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675822/
https://ncbi.nlm.nih.gov/pubmed/26636950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.09.030
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