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The Influence of Crowding Conditions on the Thermodynamic Feasibility of Metabolic Pathways

Intracellular reactions are carried out in a crowded medium where the macromolecules occupy ∼40% of the total volume. This decrease in the available volume affects the activity of the reactants. Scaled particle theory is used for the estimation of the activity coefficients of the metabolites, and th...

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Detalles Bibliográficos
Publicado en:Biophys J
Main Authors: Angeles-Martinez, Liliana, Theodoropoulos, Constantinos
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675822/
https://ncbi.nlm.nih.gov/pubmed/26636950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.09.030
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