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Network Thermodynamic Curation of Human and Yeast Genome-Scale Metabolic Models

Genome-scale models are used for an ever-widening range of applications. Although there has been much focus on specifying the stoichiometric matrix, the predictive power of genome-scale models equally depends on reaction directions. Two-thirds of reactions in the two eukaryotic reconstructions Homo...

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Autori principali: Martínez, Verónica S., Quek, Lake-Ee, Nielsen, Lars K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104063/
https://ncbi.nlm.nih.gov/pubmed/25028891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.05.029
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