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Quantitative Assessment of Thermodynamic Constraints on the Solution Space of Genome-Scale Metabolic Models

Constraint-based methods provide powerful computational techniques to allow understanding and prediction of cellular behavior. These methods rely on physiochemical constraints to eliminate infeasible behaviors from the space of available behaviors. One such constraint is thermodynamic feasibility, t...

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Detalhes bibliográficos
Main Authors: Hamilton, Joshua J., Dwivedi, Vivek, Reed, Jennifer L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3714879/
https://ncbi.nlm.nih.gov/pubmed/23870272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.06.011
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