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Candidate States of Helicobacter pylori's Genome-Scale Metabolic Network upon Application of “Loop Law” Thermodynamic Constraints

Constraint-based modeling has proven to be a useful tool in the analysis of biochemical networks. To date, most studies in this field have focused on the use of linear constraints, resulting from mass balance and capacity constraints, which lead to the definition of convex solution spaces. One addit...

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Autors principals: Price, Nathan D., Thiele, Ines, Palsson, Bernhard Ø.
Format: Artigo
Idioma:Inglês
Publicat: Biophysical Society 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459519/
https://ncbi.nlm.nih.gov/pubmed/16533855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.072645
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