A proof for loop-law constraints in stoichiometric metabolic networks

BACKGROUND: Constraint-based modeling is increasingly employed for metabolic network analysis. Its underlying assumption is that natural metabolic phenotypes can be predicted by adding physicochemical constraints to remove unrealistic metabolic flux solutions. The loopless-COBRA approach provides an...

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Bibliographic Details
Main Authors: Noor, Elad, Lewis, Nathan E, Milo, Ron
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3560238/
https://ncbi.nlm.nih.gov/pubmed/23146116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-6-140
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