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A proof for loop-law constraints in stoichiometric metabolic networks

BACKGROUND: Constraint-based modeling is increasingly employed for metabolic network analysis. Its underlying assumption is that natural metabolic phenotypes can be predicted by adding physicochemical constraints to remove unrealistic metabolic flux solutions. The loopless-COBRA approach provides an...

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Detalhes bibliográficos
Main Authors: Noor, Elad, Lewis, Nathan E, Milo, Ron
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3560238/
https://ncbi.nlm.nih.gov/pubmed/23146116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-6-140
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