Optimizing Polymyxin Combinations Against Resistant Gram-Negative Bacteria

Polymyxin combination therapy is increasingly used clinically. However, systematic investigations of such combinations are a relatively recent phenomenon. The emerging pharmacodynamic (PD) and pharmacokinetic (PK) data on CMS/colistin and polymyxin B suggest that caution is required with monotherapy...

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Publicado en:Infect Dis Ther
Autores principales: Bergen, Phillip J., Bulman, Zackery P., Landersdorfer, Cornelia B., Smith, Nicholas, Lenhard, Justin R., Bulitta, Jürgen B., Nation, Roger L., Li, Jian, Tsuji, Brian T.
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer Healthcare 2015
Materias:
Review
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675771/
https://ncbi.nlm.nih.gov/pubmed/26645096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40121-015-0093-7
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