Successful treatment of canine leukocyte adhesion deficiency by foamy virus vectors

Recent successes in treating genetic immunodeficiencies have demonstrated the therapeutic potential of stem cell gene therapy(1–4). However, the use of gammaretroviral vectors in these trials led to insertional activation of nearby oncogenes and leukemias in some study subjects, prompting studies of...

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Vydáno v:Nat Med
Hlavní autoři: Bauer, Thomas R, Allen, James M, Hai, Mehreen, Tuschong, Laura M, Khan, Iram F, Olson, Erik M, Adler, Rima L, Burkholder, Tanya H, Gu, Yu-chen, Russell, David W, Hickstein, Dennis D
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675671/
https://ncbi.nlm.nih.gov/pubmed/18157138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1695
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