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Successful treatment of canine leukocyte adhesion deficiency by foamy virus vectors

Recent successes in treating genetic immunodeficiencies have demonstrated the therapeutic potential of stem cell gene therapy(1–4). However, the use of gammaretroviral vectors in these trials led to insertional activation of nearby oncogenes and leukemias in some study subjects, prompting studies of...

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Detalhes bibliográficos
Publicado no:Nat Med
Main Authors: Bauer, Thomas R, Allen, James M, Hai, Mehreen, Tuschong, Laura M, Khan, Iram F, Olson, Erik M, Adler, Rima L, Burkholder, Tanya H, Gu, Yu-chen, Russell, David W, Hickstein, Dennis D
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675671/
https://ncbi.nlm.nih.gov/pubmed/18157138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1695
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