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Variations in telomere maintenance and the role of telomerase inhibition in gastrointestinal cancer

Immortalization is an important step toward the malignant transformation of human cells and is critically dependent upon telomere maintenance. There are two known mechanisms to maintain human telomeres. The process of telomere maintenance is either mediated through activation of the enzyme telomeras...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Pharmgenomics Pers Med
मुख्य लेखक: Heeg, Steffen
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Dove Medical Press 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675635/
https://ncbi.nlm.nih.gov/pubmed/26675332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PGPM.S52808
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