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Variations in telomere maintenance and the role of telomerase inhibition in gastrointestinal cancer

Immortalization is an important step toward the malignant transformation of human cells and is critically dependent upon telomere maintenance. There are two known mechanisms to maintain human telomeres. The process of telomere maintenance is either mediated through activation of the enzyme telomeras...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Pharmgenomics Pers Med
Glavni avtor: Heeg, Steffen
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675635/
https://ncbi.nlm.nih.gov/pubmed/26675332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PGPM.S52808
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