Variation in the Phosphoinositide 3-Kinase Gamma Gene Affects Plasma HDL-Cholesterol without Modification of Metabolic or Inflammatory Markers

OBJECTIVE: Phosphoinositide 3-kinase γ (PI3Kγ) is a G-protein-coupled receptor-activated lipid kinase mainly expressed in leukocytes and cells of the cardiovascular system. PI3Kγ plays an important signaling role in inflammatory processes. Since subclinical inflammation is a hallmark of atherosclero...

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Опубликовано в: :PLoS One
Главные авторы: Kächele, Martin, Hennige, Anita M., Machann, Jürgen, Hieronimus, Anja, Lamprinou, Apostolia, Machicao, Fausto, Schick, Fritz, Fritsche, Andreas, Stefan, Norbert, Nürnberg, Bernd, Häring, Hans-Ulrich, Staiger, Harald
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2015
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675530/
https://ncbi.nlm.nih.gov/pubmed/26658747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144494
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