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Role of Intrinsic and Extrinsic Factors in the Regulation of the Mitotic Checkpoint Kinase Bub1

The spindle assembly checkpoint (SAC) monitors microtubule attachment to kinetochores to ensure accurate sister chromatid segregation during mitosis. The SAC members Bub1 and BubR1 are paralogs that underwent significant functional specializations during evolution. We report an in-depth characteriza...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Breit, Claudia, Bange, Tanja, Petrovic, Arsen, Weir, John R., Müller, Franziska, Vogt, Doro, Musacchio, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675524/
https://ncbi.nlm.nih.gov/pubmed/26658523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144673
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