MALDI Imaging Mass Spectrometry Spatially Maps Age-Related Deamidation and Truncation of Human Lens Aquaporin-0

PURPOSE: To spatially map human lens Aquaporin-0 (AQP0) protein modifications, including lipidation, truncation, and deamidation, from birth through middle age using matrix-assisted laser desorption ionization (MALDI) imaging mass spectrometry (IMS). METHODS: Human lens sections were water-washed to...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Invest Ophthalmol Vis Sci
Prif Awduron: Wenke, Jamie L., Rose, Kristie L., Spraggins, Jeffrey M., Schey, Kevin L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Association for Research in Vision and Ophthalmology 2015
Pynciau:
Lens
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675204/
https://ncbi.nlm.nih.gov/pubmed/26574799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-18117
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg