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MALDI Imaging Mass Spectrometry Spatially Maps Age-Related Deamidation and Truncation of Human Lens Aquaporin-0
PURPOSE: To spatially map human lens Aquaporin-0 (AQP0) protein modifications, including lipidation, truncation, and deamidation, from birth through middle age using matrix-assisted laser desorption ionization (MALDI) imaging mass spectrometry (IMS). METHODS: Human lens sections were water-washed to...
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| Publicado no: | Invest Ophthalmol Vis Sci |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Association for Research in Vision and Ophthalmology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4675204/ https://ncbi.nlm.nih.gov/pubmed/26574799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-18117 |
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