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Age-Related Changes in the Spatial Distribution of Human Lens α-Crystallin Products by MALDI Imaging Mass Spectrometry

PURPOSE: To develop a protocol for MALDI (matrix-assisted laser desorption ionization) imaging mass spectrometry for mapping the distributions of α-crystallin and its modified forms in human lens tissue as a function of lens age and cataract. METHODS: Frozen human lenses were cryosectioned equatoria...

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Detalles Bibliográficos
Main Authors: Grey, Angus C., Schey, Kevin L.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760347/
https://ncbi.nlm.nih.gov/pubmed/19387068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.09-3522
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