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Spatially Directed Proteomics of the Human Lens Outer Cortex Reveals an Intermediate Filament Switch Associated With the Remodeling Zone

PURPOSE: To quantify protein changes in the morphologically distinct remodeling zone (RZ) and adjacent regions of the human lens outer cortex using spatially directed quantitative proteomics. METHODS: Lightly fixed human lens sections were deparaffinized and membranes labeled with fluorescent wheat...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Wenke, Jamie L., McDonald, W. Hayes, Schey, Kevin L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991037/
https://ncbi.nlm.nih.gov/pubmed/27537260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-19791
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