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SUMOylation of AMPKα1 by PIAS4 specifically regulates mTORC1 signalling
AMP-activated protein kinase (AMPK) inhibits several anabolic pathways such as fatty acid and protein synthesis, and identification of AMPK substrate specificity would be useful to understand its role in particular cellular processes and develop strategies to modulate AMPK activity in a substrate-sp...
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| Publicat a: | Nat Commun |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Pub. Group
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4674823/ https://ncbi.nlm.nih.gov/pubmed/26616021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9979 |
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