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The Stabilization of Amorphous Zopiclone in an Amorphous Solid Dispersion

Zopiclone is a poorly soluble psychotherapeutic agent. The aim of this study was to prepare and characterize an amorphous form of zopiclone as well as the characterization and performance of a stable amorphous solid dispersion. The amorphous form was prepared by the well-known method of quench-cooli...

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Détails bibliographiques
Publié dans:AAPS PharmSciTech
Auteurs principaux: Milne, Marnus, Liebenberg, Wilna, Aucamp, Marique
Format: Artigo
Langue:Inglês
Publié: Springer US 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674634/
https://ncbi.nlm.nih.gov/pubmed/25732372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-015-0302-4
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