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Probing the Interplay between Amorphous Solid Dispersion Stability and Polymer Functionality

Amorphous solid dispersions containing a polymeric component often impart improved stability against crystallization for a small molecule relative to the pure amorphous form. However, the relationship between side chain functionalities on a polymer and the ability of a polymer to stabilize against c...

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Detalhes bibliográficos
Publicado no:Mol Pharm
Main Authors: Frank, Derek S., Matzger, Adam J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6296464/
https://ncbi.nlm.nih.gov/pubmed/29924614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.8b00219
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