The Oncogenic Roles of DICER1 RNase IIIb Domain Mutations in Ovarian Sertoli-Leydig Cell Tumors()()

DICER1, an endoribonuclease required for microRNA (miRNA) biogenesis, is essential for embryogenesis and the development of many organs including ovaries. We have recently identified somatic hotspot mutations in RNase IIIb domain of DICER1 in half of ovarian Sertoli-Leydig cell tumors, a rare class...

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Gepubliceerd in:Neoplasia
Hoofdauteurs: Wang, Yemin, Chen, Jiamin, Yang, Winnie, Mo, Fan, Senz, Janine, Yap, Damian, Anglesio, Michael S., Gilks, Blake, Morin, Gregg B., Huntsman, David G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Neoplasia Press 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674484/
https://ncbi.nlm.nih.gov/pubmed/26408257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2015.08.003
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