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Microcephaly protein Asp focuses the minus ends of spindle microtubules at the pole and within the spindle

Depletion of Drosophila melanogaster Asp, an orthologue of microcephaly protein ASPM, causes spindle pole unfocusing during mitosis. However, it remains unclear how Asp contributes to pole focusing, a process that also requires the kinesin-14 motor Ncd. We show that Asp localizes to the minus ends o...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Cell Biol
Egile Nagusiak: Ito, Ami, Goshima, Gohta
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674282/
https://ncbi.nlm.nih.gov/pubmed/26644514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201507001
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