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Microcephaly protein Asp focuses the minus ends of spindle microtubules at the pole and within the spindle
Depletion of Drosophila melanogaster Asp, an orthologue of microcephaly protein ASPM, causes spindle pole unfocusing during mitosis. However, it remains unclear how Asp contributes to pole focusing, a process that also requires the kinesin-14 motor Ncd. We show that Asp localizes to the minus ends o...
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| Publié dans: | J Cell Biol |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Rockefeller University Press
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4674282/ https://ncbi.nlm.nih.gov/pubmed/26644514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201507001 |
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