Microtubule minus-end regulation at spindle poles by an ASPM-katanin complex

ASPM/Asp/ASPM-1 is a microcephaly-associated protein family that regulates spindle architecture, but the underlying mechanism is poorly understood. Here, we show that ASPM forms a complex with another protein linked to microcephaly, the microtubule severing ATPase katanin. ASPM and katanin localize...

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Udgivet i:Nat Cell Biol
Main Authors: Jiang, Kai, Rezabkova, Lenka, Hua, Shasha, Liu, Qingyang, Capitani, Guido, Altelaar, A. F. Maarten, Heck, Albert J. R., Kammerer, Richard A., Steinmetz, Michel O., Akhmanova, Anna
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5458804/
https://ncbi.nlm.nih.gov/pubmed/28436967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3511
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