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Microtubule minus-end regulation at spindle poles by an ASPM-katanin complex
ASPM/Asp/ASPM-1 is a microcephaly-associated protein family that regulates spindle architecture, but the underlying mechanism is poorly understood. Here, we show that ASPM forms a complex with another protein linked to microcephaly, the microtubule severing ATPase katanin. ASPM and katanin localize...
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| Veröffentlicht in: | Nat Cell Biol |
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| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5458804/ https://ncbi.nlm.nih.gov/pubmed/28436967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3511 |
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