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Caveolin-1 regulates osteoclast differentiation by suppressing cFms degradation

Caveolae are flask-shaped cell-surface membranes, which consist of cholesterol, sphingolipids and caveolin proteins. In a microarray analysis, we found that caveolin-1 (Cav-1) was upregulated by receptor activator of NFκB ligand (RANKL), the osteoclast differentiation factor. Silencing of Cav-1 inhi...

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Detalhes bibliográficos
Publicado no:Exp Mol Med
Main Authors: Lee, Yong Deok, Yoon, Soo-Hyun, Ji, Eunhee, Kim, Hong-Hee
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673477/
https://ncbi.nlm.nih.gov/pubmed/26514084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2015.77
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