Oral nano-delivery of anticancer ginsenoside 25-OCH(3)-PPD, a natural inhibitor of the MDM2 oncogene: Nanoparticle preparation, characterization, in vitro and in vivo anti-prostate cancer activity, and mechanisms of action

The Mouse Double Minute 2 (MDM2) oncogene plays a critical role in cancer development and progression through p53-dependent and p53-independent mechanisms. Both natural and synthetic MDM2 inhibitors have been shown anticancer activity against several human cancers. We have recently identified a nove...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Voruganti, Sukesh, Qin, Jiang-Jiang, Sarkar, Sushanta, Nag, Subhasree, Walbi, Ismail A., Wang, Shu, Zhao, Yuqing, Wang, Wei, Zhang, Ruiwen
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2015
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673272/
https://ncbi.nlm.nih.gov/pubmed/26041888
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