Ataxin-3 like (ATXN3L), a member of the Josephin family of deubiquitinating enzymes, promotes breast cancer proliferation by deubiquitinating Krüppel-like factor 5 (KLF5)

The Krüppel-like factor 5 (KLF5) has been suggested to promote breast cell proliferation, survival and tumorigenesis. KLF5 protein degradation is increased by several E3 ubiquitin ligases, including WWP1 and SCF(Fbw7), through the ubiquitin-proteasome pathway. However, the deubiquitinase (DUB) of KL...

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Publicado en:Oncotarget
Main Authors: Ge, Fei, Chen, Wenlin, Qin, Junying, Zhou, Zhongmei, Liu, Rong, Liu, Linlin, Tan, Jing, Zou, Tianning, Li, Hongyuan, Ren, Guosheng, Chen, Ceshi
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2015
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673271/
https://ncbi.nlm.nih.gov/pubmed/26079537
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